Synthivan Tablet (30’s)
Synthivan Tablet (30’s) is a combination medication that contains Atazanavir (300mg) and Ritonavir (100mg), primarily used in the management of HIV-1 infection. This powerful antiretroviral therapy works by inhibiting the replication of the virus, thereby helping to control the viral load in the body. Atazanavir is a protease inhibitor that targets the HIV protease enzyme, while Ritonavir acts as a booster, enhancing the effectiveness of Atazanavir by slowing its metabolism. Together, they form a potent regimen that aids in improving the immune system’s function and reducing the risk of HIV-related complications. Synthivan is typically prescribed as part of a comprehensive treatment plan that may include other antiretroviral agents, and it is essential for patients to adhere to their prescribed regimen to achieve optimal results.
Essential Drug Facts
| Dosage form | Oral Tablet |
|---|---|
| Habit Forming | No |
| Systemic Category | Infectious Disease Drugs |
What are the Indication / Medical Uses of Synthivan Tablet (30’s)
The primary medical uses of Synthivan Tablet (30's) include the treatment of HIV-1 infection in adults and children over the age of 6. It is indicated for patients who are either treatment-naive or have previously received antiretroviral therapy. By effectively reducing the viral load, Synthivan helps to prevent the progression of HIV to AIDS, thereby improving the quality of life for those living with the virus. Additionally, it may be used in combination with other medications to enhance the overall efficacy of HIV treatment regimens.
How Does Synthivan Tablet (30’s) Benefit You?
Synthivan Tablet (30's) offers several benefits for patients living with HIV. By effectively controlling the viral load, it helps to maintain a healthier immune system, reducing the risk of opportunistic infections and other complications associated with HIV. Patients taking Synthivan may experience improved overall health, increased energy levels, and a better quality of life. Furthermore, adherence to this medication can lead to undetectable viral loads, which significantly lowers the risk of HIV transmission to sexual partners, thus contributing to public health efforts in combating the spread of the virus.
.svg)
Synthivan Tablet (30’s) Action Mechanism
The action mechanism of Synthivan Tablet (30's) involves the inhibition of the HIV protease enzyme, which is crucial for the virus's replication process. Atazanavir binds to the active site of the protease, preventing the cleavage of viral polyproteins into functional proteins necessary for the assembly of new virions. Ritonavir enhances the pharmacokinetics of Atazanavir by inhibiting the cytochrome P450 3A4 enzyme, which metabolizes Atazanavir, allowing for higher and more sustained drug levels in the bloodstream. This synergistic effect results in a more effective suppression of the HIV virus, leading to better treatment outcomes for patients.
How should Synthivan Tablet (30’s) be used
To use Synthivan Tablet (30's) properly, it is essential to follow the dosage instructions provided by a healthcare professional. Typically, the recommended dosage is one tablet taken once daily with food to enhance absorption. It is crucial to take the medication at the same time each day to maintain consistent drug levels in the body. Patients should not alter the dosage or stop taking the medication without consulting their healthcare provider, as this may lead to treatment failure or increased viral resistance.
When is the best time to take Synthivan Tablet (30’s) ?
The best time to take Synthivan Tablet (30's) is with a meal, as food significantly enhances the absorption of Atazanavir. Taking the medication at the same time each day helps to establish a routine, making it easier for patients to remember their doses. Consistency in timing is vital for maintaining effective drug levels in the body, which is essential for optimal viral suppression and overall treatment success.
How does it affect me if I overdose?
In the event of an overdose of Synthivan Tablet (30's), patients may experience symptoms such as nausea, vomiting, abdominal pain, and diarrhea. Severe cases could lead to more serious complications, including liver toxicity or cardiac issues. If an overdose is suspected, it is crucial to seek immediate medical attention to manage the situation effectively and mitigate any potential risks associated with excessive drug intake.
.svg)
How does it affect me if I miss a dose?
If a dose of Synthivan Tablet (30's) is missed, patients should take the missed dose as soon as they remember, provided it is not close to the time of the next scheduled dose. In such cases, the missed dose should be skipped, and the regular dosing schedule should be resumed. Patients should not take two doses at once to make up for a missed dose, as this could increase the risk of side effects and complications.
Drug Adverse Reactions of Synthivan Tablet (30’s)
Possible side effects and adverse reactions of Synthivan Tablet (30's) may include gastrointestinal disturbances such as nausea, diarrhea, and abdominal pain. Other common side effects may include headache, fatigue, and skin rashes. In rare cases, more severe reactions such as liver problems, changes in heart rhythm, or allergic reactions may occur. Patients should report any unusual or severe symptoms to their healthcare provider promptly to ensure appropriate management.
Synthivan Tablet (30’s) Tablet is contraindicated in following conditions
Synthivan Tablet (30's) is contraindicated in patients with a known hypersensitivity to Atazanavir, Ritonavir, or any of the excipients in the formulation. It should also be avoided in individuals with severe liver impairment or those taking certain medications that may interact adversely with the components of Synthivan. A thorough medical history and medication review are essential to determine the appropriateness of this treatment for each patient.
Synthivan Tablet (30’s) Safety Warnings and Precautions
The consumption of alcohol while taking Atazanavir and Ritonavir is not recommended, as it can increase the risk of liver toxicity and may interfere with the effectiveness of the medications.
Individuals with a known allergy to Atazanavir, Ritonavir, or any of their components should avoid using these medications, as they can cause severe allergic reactions.
Atazanavir and Ritonavir may pose risks during pregnancy, and their use should be carefully considered and monitored by a healthcare provider to weigh the benefits against potential risks to the fetus.
The safety and efficacy of Atazanavir and Ritonavir in children have not been fully established, and their use should be guided by a healthcare provider familiar with pediatric HIV treatment.
Both Atazanavir and Ritonavir can be excreted in breast milk, and while the effects on a nursing infant are not fully understood, it is generally recommended to consult a healthcare professional before using these medications while breastfeeding.
Atazanavir and Ritonavir may cause dizziness or fatigue in some individuals, so caution is advised when driving or operating heavy machinery until the effects of the medication are known.
Patients with renal impairment may require dose adjustments and close monitoring while taking Atazanavir and Ritonavir, as these medications can affect kidney function.
Individuals with pre-existing lung conditions should be monitored closely while taking these medications, as respiratory issues may arise.
Atazanavir and Ritonavir are contraindicated in patients with severe liver impairment, as they can exacerbate liver conditions and lead to serious complications.
Patients with pre-existing heart conditions should use Atazanavir and Ritonavir with caution, as these medications can potentially affect heart rhythm and function.
Interactions between Synthivan Tablet (30’s)
Potential drug interactions with Synthivan Tablet (30's) can occur with various medications, including certain antibiotics, antifungals, and medications for seizures or heart conditions. These interactions may affect the metabolism of Atazanavir and Ritonavir, leading to either increased side effects or reduced effectiveness of the treatment. Patients should inform their healthcare provider of all medications they are taking to avoid potential interactions and ensure safe use.
How to store and dispose of Synthivan Tablet (30’s)
To store Synthivan Tablet (30's) properly, keep it in a cool, dry place away from direct sunlight and moisture. The medication should be stored at room temperature, ideally between 20°C to 25°C (68°F to 77°F). It is important to keep the tablets out of reach of children and pets. For disposal, unused or expired medications should be returned to a pharmacy or disposed of in accordance with local regulations to prevent environmental contamination.
Here are a few quick tips for Synthivan Tablet (30’s)
Here are a few quick tips for using Synthivan Tablet (30's) effectively and safely: always take the medication with food to enhance absorption, maintain a consistent daily schedule to avoid missed doses, and keep track of any side effects to report to your healthcare provider. Regular follow-up appointments are essential for monitoring your health and adjusting treatment as needed. Additionally, inform your healthcare provider of any new medications or supplements you plan to take.
Parameters that should be monitored Synthivan Tablet (30’s)
While using Synthivan Tablet (30's), it is important to monitor several parameters, including liver function tests, kidney function, and viral load. Regular blood tests will help assess the effectiveness of the treatment and detect any potential side effects early. Patients should also be vigilant for any signs of allergic reactions or severe side effects and report them to their healthcare provider immediately.
Considerations related to diet Synthivan Tablet (30’s)
Dietary considerations while using Synthivan Tablet (30's) include maintaining a balanced diet and avoiding high-fat meals, which can affect the absorption of Atazanavir. Patients should also stay well-hydrated and limit alcohol intake to reduce the risk of liver toxicity. It is advisable to consult a healthcare provider or a nutritionist for personalized dietary recommendations while on this medication.
Question and Answer (FAQ)
Q: What is Synthivan Tablet used for?
A: Synthivan Tablet is used for the treatment of HIV-1 infection in adults and children over the age of 6.
Q: How should I take Synthivan Tablet?
A: Take Synthivan Tablet once daily with food, at the same time each day, as directed by your healthcare provider.
Q: What are the side effects of Synthivan Tablet?
A: Common side effects may include nausea, diarrhea, headache, and fatigue. Severe reactions may include liver problems or allergic reactions.
Q: Can I take Synthivan Tablet if I am pregnant?
A: The use of Synthivan Tablet during pregnancy should be approached with caution, and it is essential to discuss risks and benefits with your healthcare provider.
Q: Is it safe to breastfeed while taking Synthivan Tablet?
A: Breastfeeding while on Synthivan Tablet should be approached with caution, as the medication can be excreted in breast milk.
Q: What should I do if I miss a dose of Synthivan Tablet?
A: If you miss a dose, take it as soon as you remember unless it is close to the next dose. Do not take two doses at once.
Q: What happens if I overdose on Synthivan Tablet?
A: An overdose may cause symptoms like nausea, vomiting, and abdominal pain. Seek immediate medical attention if an overdose is suspected.
Q: Are there any drug interactions with Synthivan Tablet?
A: Yes, Synthivan Tablet can interact with various medications, including certain antibiotics and antifungals. Always inform your healthcare provider of all medications you are taking.
Q: How should I store Synthivan Tablet?
A: Store Synthivan Tablet in a cool, dry place away from direct sunlight and moisture, and keep it out of reach of children.
Q: What dietary restrictions should I follow while taking Synthivan Tablet?
A: Avoid high-fat meals that can affect the absorption of Atazanavir, and limit alcohol intake to reduce the risk of liver toxicity.
Reviews
There are no reviews yet.