Name: Folitrax 25MG Injection (1ml)
SKU: PL1363
Availability: InStock

Folitrax 25MG Injection (1ml)

Folitrax 25MG Injection (1ml) is a pharmaceutical preparation containing Methotrexate, a potent antimetabolite and immunosuppressant agent. This medication is primarily used in the treatment of various conditions, including certain types of cancer, autoimmune diseases, and ectopic pregnancies. Methotrexate works by inhibiting the metabolism of folic acid, which is essential for DNA synthesis and cell division. The injection form allows for rapid absorption and effectiveness, making it suitable for patients who may have difficulty with oral medications. Folitrax is often administered under the supervision of a healthcare professional, ensuring that patients receive the correct dosage tailored to their specific medical needs. The composition of Folitrax includes Methotrexate at a concentration of 25mg per 1ml, along with other excipients that facilitate its delivery and stability. This drug is a critical component in modern therapeutic regimens, providing significant benefits in managing complex health conditions.

Essential Drug Facts

Dosage form	Iv(Intravenous) Injection
Chemical Class	Glutamic Acid Derivative
Habit Forming	No
Systemic Category	Allergy & Immune System
Action Class	Antimetabolite- Methotrexate

What are the Indication / Medical Uses of Folitrax 25MG Injection (1ml)

Folitrax 25MG Injection is indicated for a variety of medical uses, including the treatment of certain cancers such as leukemia, lymphoma, and osteosarcoma. It is also utilized in managing autoimmune disorders like rheumatoid arthritis and psoriasis, where it helps to reduce inflammation and suppress the immune response. Additionally, Folitrax is indicated for the management of ectopic pregnancies, where it helps to terminate the pregnancy safely. The versatility of Methotrexate in treating both malignancies and autoimmune conditions makes Folitrax an essential medication in oncology and rheumatology.

How Does Folitrax 25MG Injection (1ml) Benefit You?

The benefits of Folitrax 25MG Injection for patients are substantial. By effectively targeting rapidly dividing cells, Methotrexate can help shrink tumors and manage symptoms associated with autoimmune diseases. Patients often experience a reduction in pain and inflammation, leading to improved quality of life. Furthermore, the injection form allows for precise dosing and rapid onset of action, which is particularly beneficial in acute situations. Regular use of Folitrax can lead to long-term remission in chronic conditions, making it a valuable option for ongoing management.

Folitrax 25MG Injection (1ml) Action Mechanism

Folitrax 25MG Injection works by inhibiting the enzyme dihydrofolate reductase, which is crucial for the conversion of folate into its active form. This action disrupts the synthesis of nucleic acids, ultimately leading to the inhibition of cell division and growth. In cancer treatment, this mechanism helps to slow down or stop the proliferation of malignant cells. In autoimmune diseases, the immunosuppressive effects of Methotrexate help to reduce the overactive immune response that contributes to inflammation and tissue damage. This dual action makes Folitrax a powerful therapeutic agent in various medical contexts.

How should Folitrax 25MG Injection (1ml) be used

Folitrax 25MG Injection should be used as directed by a healthcare professional. The dosage and frequency of administration depend on the specific condition being treated, the patient's overall health, and their response to the medication. Typically, it is administered via subcutaneous or intramuscular injection, and patients are advised to follow their healthcare provider's instructions closely. It is crucial to monitor for any side effects and report them to a healthcare provider promptly. Patients should not self-adjust their dosage without consulting their doctor.

When is the best time to take Folitrax 25MG Injection (1ml) ?

The best time to take Folitrax 25MG Injection is determined by the treatment plan established by a healthcare provider. It is often administered once a week for chronic conditions, while cancer treatment regimens may vary. Patients should adhere to the schedule provided by their healthcare professional to ensure optimal effectiveness and minimize the risk of side effects. Consistency in timing can also help maintain stable drug levels in the body.

How does it affect me if I overdose?

In the event of an overdose of Folitrax 25MG Injection, patients may experience severe side effects, including gastrointestinal distress, liver toxicity, and bone marrow suppression. Symptoms of overdose can include nausea, vomiting, diarrhea, and increased susceptibility to infections due to lowered white blood cell counts. It is critical to seek immediate medical attention if an overdose is suspected, as timely intervention can mitigate serious health risks.

How does it affect me if I miss a dose?

If a dose of Folitrax 25MG Injection is missed, patients should contact their healthcare provider for guidance. Depending on the timing of the missed dose, the provider may recommend administering the dose as soon as possible or skipping it if it is close to the time for the next scheduled dose. Missing a dose can lead to fluctuations in drug levels, potentially affecting treatment efficacy, so it is important to follow the provider's advice closely.

Drug Adverse Reactions of Folitrax 25MG Injection (1ml)

Possible side effects and adverse reactions of Folitrax 25MG Injection can include nausea, vomiting, fatigue, and increased risk of infections due to immunosuppression. Some patients may also experience liver toxicity, mouth sores, or skin rashes. It is essential for patients to report any unusual symptoms or severe side effects to their healthcare provider immediately, as some reactions may require medical intervention or adjustment of the treatment regimen.

Folitrax 25MG Injection (1ml) Tablet is contraindicated in following conditions

Folitrax 25MG Injection is contraindicated in several conditions, including pregnancy, breastfeeding, and in patients with known hypersensitivity to Methotrexate or any of its components. It should also be avoided in individuals with severe liver or kidney impairment, as these conditions can exacerbate the drug's toxicity. Patients with active infections or those who are immunocompromised should also refrain from using this medication unless specifically directed by a healthcare provider.

Folitrax 25MG Injection (1ml) Safety Warnings and Precautions

Alcohol:UNSAFE

Alcohol can increase the risk of liver toxicity when taken with Methotrexate, and its consumption should be avoided during treatment.

Allergy:CAUTION

Patients with a known allergy to Methotrexate or any of its components should avoid this medication, as it may lead to severe allergic reactions.

Pregnancy:UNSAFE

Methotrexate is known to cause fetal harm and is contraindicated during pregnancy due to its teratogenic effects, which can lead to severe birth defects or miscarriage.

Children:CAUTION

While Methotrexate can be used in pediatric patients for certain conditions, careful monitoring is required due to the risk of toxicity and the need for appropriate dosing adjustments.

Lactation:UNSAFE

Methotrexate is excreted in breast milk and may affect a nursing infant, potentially leading to serious side effects.

Drive:CAUTION

Methotrexate may cause dizziness or fatigue in some patients, which can impair the ability to drive or operate machinery safely.

Kidney:CAUTION

Patients with impaired kidney function may experience increased toxicity from Methotrexate, necessitating dose adjustments and close monitoring of renal function.

Lungs:CAUTION

Methotrexate can cause pulmonary toxicity, including pneumonitis, and patients with pre-existing lung conditions should be monitored closely.

Liver:CAUTION

Methotrexate can cause liver toxicity, and patients with pre-existing liver disease should be closely monitored, as they are at higher risk for adverse effects.

Heart:CAUTION

Patients with pre-existing heart conditions should use Methotrexate with caution, as it may exacerbate certain cardiovascular issues.

Interactions between Folitrax 25MG Injection (1ml)

Folitrax 25MG Injection may interact with several other medications, potentially altering their effectiveness or increasing the risk of side effects. Notable interactions include nonsteroidal anti-inflammatory drugs (NSAIDs), which can increase the risk of gastrointestinal toxicity, and other immunosuppressants, which may enhance the risk of infections. Patients should inform their healthcare provider of all medications, supplements, and herbal products they are taking to avoid potential interactions.

How to store and dispose of Folitrax 25MG Injection (1ml)

To store Folitrax 25MG Injection properly, it should be kept in a cool, dry place away from direct sunlight and moisture. The medication should be stored at room temperature and kept out of reach of children. Unused or expired injections should be disposed of according to local regulations, typically by returning them to a pharmacy or following specific disposal guidelines to prevent environmental contamination.

Here are a few quick tips for Folitrax 25MG Injection (1ml)

Here are a few quick tips for using Folitrax 25MG Injection effectively and safely: Always follow your healthcare provider's instructions regarding dosage and administration. Keep a record of your injection schedule to avoid missed doses. Monitor for any side effects and report them to your healthcare provider promptly. Stay hydrated and maintain a balanced diet to support your overall health during treatment. Regularly attend follow-up appointments for blood tests and monitoring of liver and kidney function.

Parameters that should be monitored Folitrax 25MG Injection (1ml)

While using Folitrax 25MG Injection, it is essential to monitor specific parameters, including complete blood counts to assess for bone marrow suppression, liver function tests to detect hepatotoxicity, and renal function tests to ensure proper drug clearance. Regular monitoring helps to identify any potential complications early and allows for timely intervention if necessary.

Considerations related to diet Folitrax 25MG Injection (1ml)

Dietary considerations while using Folitrax 25MG Injection include maintaining a well-balanced diet rich in fruits, vegetables, and whole grains. Patients should avoid excessive alcohol consumption, as it can increase the risk of liver toxicity. Additionally, it is advisable to discuss any dietary supplements or herbal products with a healthcare provider, as some may interact with Methotrexate.