Evermil 20MG Tablet (10’s)
Evermil 20MG Tablet (10’s) is a pharmaceutical product containing Everolimus, a potent immunosuppressant and anti-cancer agent. This medication is primarily used in the treatment of various types of cancers, including renal cell carcinoma, and is also indicated for patients who have undergone organ transplants to prevent rejection. Evermil works by inhibiting the mTOR (mammalian target of rapamycin) pathway, which plays a crucial role in cell growth, proliferation, and survival. Each tablet contains 20 mg of Everolimus, and it is essential for patients to follow their healthcare provider’s instructions regarding its use. The drug is available in a blister pack of 10 tablets, making it convenient for patients to manage their treatment regimen. Evermil is recognized for its effectiveness in controlling tumor growth and improving the quality of life for patients with specific malignancies, as well as for its role in maintaining organ transplant success.
Essential Drug Facts
| Dosage form | Oral Tablet |
|---|---|
| Chemical Class | Macrolide Lactams |
| Habit Forming | No |
| Systemic Category | Allergy & Immune System |
| Action Class | Immunosuppressant- Calcineurin inhibitors |
What are the Indication / Medical Uses of Evermil 20MG Tablet (10’s)
Evermil 20MG Tablet (10's) is indicated for the treatment of advanced renal cell carcinoma, particularly in patients who have received prior anti-angiogenic therapy. Additionally, it is used in the management of neuroendocrine tumors originating from the pancreas and in the prevention of organ rejection in kidney transplant recipients. The drug is also effective in treating certain types of breast cancer and other malignancies, making it a versatile option in oncology and transplant medicine.
How Does Evermil 20MG Tablet (10’s) Benefit You?
The benefits of Evermil 20MG Tablet (10's) for patients include its ability to slow down the progression of cancer by inhibiting tumor cell growth and proliferation. For transplant patients, it significantly reduces the risk of organ rejection, thereby enhancing the success rate of transplants. Patients may experience improved overall health and quality of life as the drug effectively manages their conditions. Furthermore, Evermil's targeted action on the mTOR pathway allows for a more focused treatment approach, minimizing damage to healthy cells compared to traditional chemotherapy.
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Evermil 20MG Tablet (10’s) Action Mechanism
Evermil 20MG Tablet (10's) exerts its therapeutic effects by inhibiting the mTOR signaling pathway, which is crucial for cell cycle progression and metabolism. By blocking this pathway, Everolimus disrupts the growth and proliferation of cancer cells, leading to reduced tumor size and growth rate. In transplant patients, the drug suppresses the immune response, preventing the body from rejecting the transplanted organ. This dual action makes Evermil a valuable treatment option in both oncology and transplant medicine.
How should Evermil 20MG Tablet (10’s) be used
To use Evermil 20MG Tablet (10's) properly, patients should take the medication exactly as prescribed by their healthcare provider. It is typically taken once daily, with or without food, and should be swallowed whole with a glass of water. Patients should not crush or chew the tablet, as this may affect the drug's efficacy. Consistency in timing is important, so it is advisable to take the tablet at the same time each day to maintain stable drug levels in the body.
When is the best time to take Evermil 20MG Tablet (10’s) ?
The best time to take Evermil 20MG Tablet (10's) is usually in the morning or evening, depending on the healthcare provider's recommendation. It is important to establish a routine, as taking the medication at the same time each day helps ensure optimal absorption and effectiveness. Patients should avoid taking the tablet with high-fat meals, as this may alter the drug's absorption.
How does it affect me if I overdose?
In the event of an overdose of Evermil 20MG Tablet (10's), patients may experience severe side effects, including nausea, vomiting, diarrhea, and potential liver toxicity. Overdose can lead to significant immunosuppression, increasing the risk of infections and other complications. If an overdose is suspected, it is crucial to seek immediate medical attention to manage the situation effectively.
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How does it affect me if I miss a dose?
If a dose of Evermil 20MG Tablet (10's) is missed, patients should take it as soon as they remember. However, if it is almost time for the next scheduled dose, they should skip the missed dose and continue with their regular dosing schedule. Patients should not double the dose to make up for a missed one, as this can increase the risk of side effects and complications.
Drug Adverse Reactions of Evermil 20MG Tablet (10’s)
Possible side effects and adverse reactions of Evermil 20MG Tablet (10's) may include mouth ulcers, diarrhea, nausea, fatigue, and increased risk of infections due to immunosuppression. Some patients may also experience elevated liver enzymes, hyperlipidemia, and skin rashes. It is important for patients to report any unusual symptoms to their healthcare provider promptly.
Evermil 20MG Tablet (10’s) Tablet is contraindicated in following conditions
Evermil 20MG Tablet (10's) is contraindicated in patients with a known hypersensitivity to Everolimus or any of its components. It should also be avoided in individuals with severe liver impairment, as the drug is metabolized in the liver. Additionally, patients with active infections or those who are pregnant should not use this medication due to potential risks to the fetus and the increased risk of infections.
Evermil 20MG Tablet (10’s) Safety Warnings and Precautions
The consumption of alcohol may increase the risk of side effects and should be limited while taking Evermil.
Patients with known allergies to Everolimus or any of its components should avoid this medication to prevent allergic reactions.
Everolimus can cause fetal harm and is contraindicated during pregnancy due to the potential for teratogenic effects.
The safety and efficacy of Everolimus in pediatric patients have not been established, and its use should be closely monitored.
It is not known whether Everolimus is excreted in human breast milk, and its effects on a nursing infant are unknown, so caution is advised.
Everolimus may cause dizziness or fatigue in some individuals, so caution is advised when driving or operating heavy machinery.
Patients with renal impairment may require dose adjustments and should be monitored for potential side effects.
Patients with a history of lung disease should be monitored, as Everolimus can cause pulmonary complications.
Patients with liver impairment may experience altered drug metabolism, necessitating careful monitoring and possible dose adjustments.
Patients with pre-existing heart conditions should be monitored closely, as Everolimus may exacerbate certain cardiovascular issues.
Interactions between Evermil 20MG Tablet (10’s)
Evermil 20MG Tablet (10's) may interact with several other medications, potentially altering their effectiveness or increasing the risk of side effects. Notable interactions include those with strong CYP3A4 inhibitors and inducers, which can affect the metabolism of Everolimus. Patients should inform their healthcare provider of all medications, supplements, and herbal products they are taking to avoid potential interactions.
How to store and dispose of Evermil 20MG Tablet (10’s)
To store Evermil 20MG Tablet (10's) properly, keep the medication in its original packaging at room temperature, away from moisture and direct sunlight. It is important to keep the tablets out of reach of children and pets. For disposal, unused or expired tablets should be returned to a pharmacy or disposed of in accordance with local regulations to prevent accidental ingestion.
Here are a few quick tips for Evermil 20MG Tablet (10’s)
Here are a few quick tips for using Evermil 20MG Tablet (10's) effectively and safely: always take the medication as prescribed by your healthcare provider, maintain a consistent daily schedule for taking the tablet, avoid high-fat meals that may affect absorption, and keep regular follow-up appointments for monitoring your health. Additionally, report any side effects or unusual symptoms to your doctor promptly.
Parameters that should be monitored Evermil 20MG Tablet (10’s)
While using Evermil 20MG Tablet (10's), patients should monitor specific parameters, including liver function tests, lipid levels, and signs of infection. Regular blood tests may be necessary to assess the drug's impact on the body and to ensure that it is being used safely and effectively. Patients should also be vigilant for any symptoms of adverse reactions and communicate these to their healthcare provider.
Considerations related to diet Evermil 20MG Tablet (10’s)
Dietary considerations while using Evermil 20MG Tablet (10's) include avoiding high-fat meals, which can interfere with the absorption of the medication. Patients should maintain a balanced diet rich in fruits, vegetables, and whole grains to support overall health. It is also advisable to stay hydrated and limit alcohol intake, as it may exacerbate side effects.
Question and Answer (FAQ)
Q: What is Evermil 20MG Tablet used for?
A: Evermil 20MG Tablet is used to treat advanced renal cell carcinoma and to prevent organ rejection in kidney transplant patients.
Q: How should I take Evermil 20MG Tablet?
A: Take Evermil 20MG Tablet once daily, with or without food, and swallow it whole with a glass of water.
Q: What should I do if I miss a dose of Evermil?
A: If you miss a dose, take it as soon as you remember, but skip it if it's almost time for your next dose. Do not double the dose.
Q: What are the common side effects of Evermil?
A: Common side effects include mouth ulcers, diarrhea, nausea, fatigue, and increased risk of infections.
Q: Can I take Evermil if I am pregnant?
A: No, Evermil is not recommended during pregnancy due to potential risks to the fetus.
Q: Is Evermil safe for breastfeeding mothers?
A: No, Evermil is not considered safe for breastfeeding, as it can be excreted in breast milk.
Q: Can children take Evermil 20MG Tablet?
A: Evermil should be used with caution in children, as its safety and efficacy in this population are not well established.
Q: What should I do if I overdose on Evermil?
A: If you suspect an overdose, seek immediate medical attention, as it can lead to severe side effects and complications.
Q: Are there any dietary restrictions while taking Evermil?
A: Yes, avoid high-fat meals that may affect the absorption of Evermil, and maintain a balanced diet.
Q: How should I store Evermil 20MG Tablet?
A: Store Evermil at room temperature, away from moisture and sunlight, and keep it out of reach of children.
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