Axzyb 5MG Tablet (30’s)
Axzyb 5MG Tablet, containing the active ingredient Axitinib, is a targeted therapy primarily used in the treatment of advanced renal cell carcinoma (RCC), a type of kidney cancer. This medication works by inhibiting specific proteins that promote tumor growth and blood vessel formation, thereby slowing down the progression of cancer. Each tablet contains 5 mg of Axitinib, and it is typically available in a pack of 30 tablets. Axzyb is designed for patients who have previously undergone treatment with other therapies, making it a crucial option in the management of advanced RCC. The drug is taken orally, and its effectiveness is enhanced when used as part of a comprehensive cancer treatment plan, which may include surgery, radiation, or other medications. Understanding the composition and purpose of Axzyb is essential for patients and healthcare providers alike, as it plays a significant role in improving outcomes for those battling advanced kidney cancer.

Essential Drug Facts
Dosage form | Oral Tablet |
---|---|
Chemical Class | Enzamide and Indazole Derivative |
Habit Forming | No |
Systemic Category | Oncology |
Action Class | Tyrosine kinase inhibitors |
What are the Indication / Medical Uses of Axzyb 5MG Tablet (30’s)
Axzyb 5MG Tablet is primarily indicated for the treatment of advanced renal cell carcinoma (RCC) in adults. It is particularly beneficial for patients who have experienced disease progression following prior systemic therapy. The drug is utilized in cases where the cancer has metastasized or is no longer responding to other treatments. By targeting the vascular endothelial growth factor (VEGF) pathway, Axzyb helps to inhibit tumor growth and reduce the spread of cancer cells, making it a vital component in the therapeutic arsenal against advanced RCC.
How Does Axzyb 5MG Tablet (30’s) Benefit You?
The benefits of Axzyb 5MG Tablet for patients include its ability to significantly slow the progression of advanced renal cell carcinoma, potentially leading to improved survival rates and quality of life. By targeting specific pathways involved in tumor growth, Axitinib can help shrink tumors and reduce symptoms associated with cancer. Additionally, Axzyb is often well-tolerated by patients, allowing them to maintain their daily activities while undergoing treatment. The drug's targeted action minimizes damage to healthy cells, which is a common concern with traditional chemotherapy, making it a preferred choice for many oncologists.
Axzyb 5MG Tablet (30’s) Action Mechanism
Axzyb 5MG Tablet works by selectively inhibiting the activity of certain tyrosine kinases, particularly those involved in the vascular endothelial growth factor (VEGF) signaling pathway. This action disrupts the blood supply to tumors, effectively starving them of the nutrients and oxygen they need to grow and spread. By blocking these signals, Axitinib not only slows down tumor growth but also reduces the likelihood of metastasis, making it a powerful tool in the management of advanced renal cell carcinoma. The targeted mechanism of action allows for a more focused approach to cancer treatment, which can lead to better outcomes for patients.
How should Axzyb 5MG Tablet (30’s) be used
To use Axzyb 5MG Tablet effectively, it is essential to follow the dosage instructions provided by a healthcare professional. The typical starting dose is 5 mg taken orally twice daily, with or without food. It is crucial to take the medication at the same times each day to maintain consistent levels in the bloodstream. Patients should swallow the tablet whole with a glass of water and avoid crushing or chewing it. Regular follow-up appointments with a healthcare provider are necessary to monitor the patient's response to the medication and adjust the dosage if needed.
When is the best time to take Axzyb 5MG Tablet (30’s) ?
The best time to take Axzyb 5MG Tablet is as prescribed by a healthcare provider, typically twice daily. It is advisable to take the medication at the same times each day to maintain a consistent level of the drug in the body. Patients can choose to take it with or without food, but they should be consistent with their choice to avoid fluctuations in absorption. Establishing a routine can help ensure that doses are not missed and that the treatment remains effective.
How does it affect me if I overdose?
In the event of an overdose of Axzyb 5MG Tablet, patients may experience severe side effects, including increased blood pressure, gastrointestinal issues, and potential liver dysfunction. Overdose symptoms can vary, but they may include nausea, vomiting, diarrhea, and fatigue. It is crucial to seek immediate medical attention if an overdose is suspected, as prompt intervention can help mitigate serious health risks associated with excessive dosing.
How does it affect me if I miss a dose?
If a dose of Axzyb 5MG Tablet is missed, patients should take it as soon as they remember, unless it is almost time for the next scheduled dose. In such cases, they should skip the missed dose and continue with their regular dosing schedule. Patients should not double up on doses to make up for a missed one, as this can increase the risk of side effects and complications. Consistent communication with healthcare providers is essential to manage any missed doses effectively.
Drug Adverse Reactions of Axzyb 5MG Tablet (30’s)
Possible side effects and adverse reactions of Axzyb 5MG Tablet may include hypertension, fatigue, diarrhea, nausea, and decreased appetite. Some patients may also experience hand-foot syndrome, which is characterized by redness, swelling, and pain in the palms of the hands and soles of the feet. While many side effects are manageable, it is important for patients to report any severe or persistent symptoms to their healthcare provider for appropriate management.
Axzyb 5MG Tablet (30’s) Tablet is contraindicated in following conditions
Axzyb 5MG Tablet is contraindicated in patients with a known hypersensitivity to Axitinib or any of the tablet's inactive ingredients. Additionally, it should not be used in individuals with severe liver impairment, as this can significantly affect the drug's metabolism and increase the risk of adverse effects. Patients with a history of gastrointestinal perforation or fistula should also avoid this medication due to the potential for exacerbating these conditions.
Axzyb 5MG Tablet (30’s) Safety Warnings and Precautions
The interaction between Axitinib and alcohol is not well-studied, but alcohol may exacerbate side effects such as dizziness and fatigue, so moderation is advised.
Patients with a known hypersensitivity to Axitinib or any of its components should avoid its use due to the risk of severe allergic reactions.
Axitinib may cause harm to a developing fetus, and its use during pregnancy is contraindicated due to potential teratogenic effects.
The safety and efficacy of Axitinib in pediatric patients have not been established, making it unsuitable for use in children.
It is not known whether Axitinib is excreted in human breast milk, and its effects on a nursing infant are unknown, so caution is advised when considering its use while breastfeeding.
Axitinib may cause dizziness or fatigue, which can impair the ability to drive or operate machinery safely, so caution is advised when engaging in these activities.
Patients with renal impairment may require dose adjustments, as Axitinib is primarily eliminated through the kidneys, and impaired function can lead to increased drug exposure.
Axitinib may cause pulmonary complications, including interstitial lung disease, and patients with pre-existing lung conditions should be monitored for respiratory symptoms.
Patients with hepatic impairment may experience altered drug metabolism, necessitating careful monitoring and possible dose adjustments to avoid toxicity.
Axitinib can cause hypertension and other cardiovascular effects, so patients with pre-existing heart conditions should be monitored closely during treatment.
Interactions between Axzyb 5MG Tablet (30’s)
Potential drug interactions with Axzyb 5MG Tablet include medications that affect liver enzymes, particularly those that induce or inhibit cytochrome P450 3A4. Drugs such as ketoconazole, rifampin, and certain anticonvulsants can alter the metabolism of Axitinib, leading to increased side effects or reduced efficacy. Patients should inform their healthcare provider of all medications, supplements, and herbal products they are taking to avoid potential interactions.
How to store and dispose of Axzyb 5MG Tablet (30’s)
To store Axzyb 5MG Tablet, keep it in a cool, dry place away from direct sunlight and moisture. The medication should be stored at room temperature, ideally between 20°C to 25°C (68°F to 77°F). It is important to keep the tablets out of reach of children and pets. For disposal, unused or expired Axzyb tablets should be returned to a pharmacy or disposed of in accordance with local regulations to prevent accidental ingestion or environmental contamination.
Here are a few quick tips for Axzyb 5MG Tablet (30’s)
Here are a few quick tips for using Axzyb 5MG Tablet effectively and safely: always take the medication as prescribed by your healthcare provider, maintain a consistent schedule for taking the drug, monitor your blood pressure regularly, report any unusual side effects or symptoms to your doctor, and attend all follow-up appointments for monitoring and dosage adjustments. Additionally, ensure you stay hydrated and maintain a balanced diet to support your overall health during treatment.
Parameters that should be monitored Axzyb 5MG Tablet (30’s)
While using Axzyb 5MG Tablet, it is important to monitor several parameters, including blood pressure, liver function tests, and signs of gastrointestinal complications. Regular check-ups with a healthcare provider can help ensure that any potential side effects are identified and managed promptly. Patients should also be vigilant for symptoms such as severe abdominal pain, changes in bowel habits, or respiratory issues, which may indicate complications requiring immediate medical attention.
Considerations related to diet Axzyb 5MG Tablet (30’s)
Dietary considerations while using Axzyb 5MG Tablet include maintaining a balanced diet rich in fruits, vegetables, and whole grains to support overall health. Patients should avoid excessive consumption of grapefruit and grapefruit juice, as these can interfere with the metabolism of Axitinib and increase the risk of side effects. Staying well-hydrated is also important, as it can help mitigate some gastrointestinal side effects associated with the medication.
Question and Answer (FAQ)
Q: What is Axzyb 5MG Tablet used for?
A: Axzyb 5MG Tablet is used for the treatment of advanced renal cell carcinoma (RCC) in adults.
Q: How should I take Axzyb 5MG Tablet?
A: Take Axzyb 5MG Tablet as prescribed by your healthcare provider, typically 5 mg twice daily, with or without food.
Q: What are the common side effects of Axzyb 5MG Tablet?
A: Common side effects include hypertension, fatigue, diarrhea, nausea, and decreased appetite.
Q: Can I take Axzyb 5MG Tablet if I am pregnant?
A: No, Axzyb 5MG Tablet is not recommended during pregnancy due to potential risks to the fetus.
Q: Is Axzyb 5MG Tablet safe for breastfeeding mothers?
A: No, it is not known if Axitinib is excreted in breast milk, so it is advised to avoid breastfeeding while taking this medication.
Q: What should I do if I miss a dose of Axzyb 5MG Tablet?
A: If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double up on doses.
Q: What should I do if I overdose on Axzyb 5MG Tablet?
A: Seek immediate medical attention if you suspect an overdose, as it can lead to severe side effects.
Q: Can I drink alcohol while taking Axzyb 5MG Tablet?
A: It is advisable to limit or avoid alcohol consumption while taking Axzyb, as it can exacerbate side effects.
Q: Are there any drug interactions with Axzyb 5MG Tablet?
A: Yes, Axzyb can interact with medications that affect liver enzymes, so inform your healthcare provider of all medications you are taking.
Q: How should I store Axzyb 5MG Tablet?
A: Store Axzyb 5MG Tablet in a cool, dry place away from direct sunlight and out of reach of children.
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