Asunra 400MG Tablet (6’s)
Asunra 400MG Tablet, which contains the active ingredient Deferasirox at a dosage of 400mg, is a medication primarily used for the treatment of chronic iron overload due to blood transfusions in patients with conditions such as thalassemia or sickle cell disease. This oral tablet is designed to help reduce excess iron accumulation in the body, which can lead to serious complications affecting the heart, liver, and endocrine organs. Asunra works by binding to free iron in the bloodstream, facilitating its excretion through the gastrointestinal tract. The formulation is available in a pack of six tablets, making it convenient for patients to manage their treatment regimen. Asunra is an essential part of iron chelation therapy, helping to improve the quality of life for patients suffering from iron overload while minimizing the risk of organ damage.
Essential Drug Facts
| Dosage form | Oral Tablet |
|---|---|
| Chemical Class | Triazole & benzoate derivative |
| Habit Forming | No |
| Systemic Category | Antidotes |
What are the Indication / Medical Uses of Asunra 400MG Tablet (6’s)
Asunra 400MG Tablet is indicated for the treatment of chronic iron overload in patients who have received multiple blood transfusions, particularly those with beta-thalassemia major or other anemias requiring regular transfusions. It is also used in patients with non-transfusion-dependent thalassemia who have significant iron overload. The medication is crucial for preventing complications associated with excess iron, such as heart disease, liver dysfunction, and diabetes, thereby improving overall health outcomes in affected individuals.
How Does Asunra 400MG Tablet (6’s) Benefit You?
The benefits of Asunra 400MG Tablet for patients include its ability to effectively reduce iron levels in the body, thereby preventing the long-term complications associated with iron overload. By facilitating the removal of excess iron, Asunra helps protect vital organs from damage, enhances the patient's quality of life, and may improve overall survival rates in individuals with chronic conditions requiring frequent blood transfusions. Additionally, the oral formulation offers a convenient alternative to other iron chelation therapies, making it easier for patients to adhere to their treatment plans.
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Asunra 400MG Tablet (6’s) Action Mechanism
Asunra 400MG Tablet works through a mechanism known as iron chelation, where the active ingredient Deferasirox binds to free iron in the bloodstream. This binding forms a stable complex that is then excreted from the body primarily through the feces. By reducing the levels of free iron, Asunra helps to prevent the harmful effects of iron accumulation in various organs, including the heart and liver. This action not only mitigates the risk of organ damage but also supports overall metabolic health in patients with chronic iron overload.
How should Asunra 400MG Tablet (6’s) be used
To use Asunra 400MG Tablet effectively, it is important to follow the dosage instructions provided by a healthcare professional. The typical starting dose for adults and children over the age of six is usually based on body weight, with adjustments made according to the patient's response and iron levels. The tablet should be taken once daily, preferably at the same time each day, and can be taken with or without food. It is essential to swallow the tablet whole without chewing, and if a dose is missed, it should be taken as soon as remembered unless it is close to the time for the next dose.
When is the best time to take Asunra 400MG Tablet (6’s) ?
The best time to take Asunra 400MG Tablet is typically in the morning, as this can help establish a routine and improve adherence to the medication schedule. Taking the tablet at the same time each day can also help maintain consistent levels of the drug in the bloodstream, optimizing its effectiveness in reducing iron overload. Patients should consult their healthcare provider for personalized recommendations regarding the timing of their doses.
How does it affect me if I overdose?
In the event of an overdose of Asunra 400MG Tablet, patients may experience symptoms such as gastrointestinal disturbances, including nausea, vomiting, diarrhea, and abdominal pain. Severe cases can lead to more serious complications, including kidney damage and liver dysfunction. It is crucial to seek immediate medical attention if an overdose is suspected, as timely intervention can help mitigate potential risks and complications associated with excessive intake of the medication.
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How does it affect me if I miss a dose?
If a dose of Asunra 400MG Tablet is missed, patients should take the missed dose as soon as they remember, unless it is almost time for the next scheduled dose. In such cases, the missed dose should be skipped, and the regular dosing schedule should be resumed. Patients should not take two doses at once to make up for a missed dose, as this can increase the risk of side effects and complications.
Drug Adverse Reactions of Asunra 400MG Tablet (6’s)
Asunra 400MG Tablet may cause some side effects and adverse reactions, which can vary from mild to severe. Common side effects include gastrointestinal issues such as diarrhea, nausea, and abdominal pain. Other potential adverse reactions may include skin rashes, elevated liver enzymes, and renal impairment. Patients should be monitored for these side effects, and any unusual symptoms should be reported to a healthcare provider promptly to ensure appropriate management.
Asunra 400MG Tablet (6’s) Tablet is contraindicated in following conditions
Asunra 400MG Tablet is contraindicated in certain conditions, including severe renal impairment, active gastrointestinal bleeding, and hypersensitivity to Deferasirox or any of the tablet's components. Patients with a history of allergic reactions to similar medications should also avoid using Asunra. It is essential for individuals to disclose their complete medical history to their healthcare provider to determine if Asunra is a suitable treatment option.
Asunra 400MG Tablet (6’s) Safety Warnings and Precautions
The consumption of alcohol while taking deferasirox is not recommended, as it may increase the risk of liver damage and other adverse effects.
Individuals with a known allergy to deferasirox or any of its components should avoid using this medication, as it may cause severe allergic reactions.
Deferasirox may pose risks during pregnancy, and its effects on fetal development are not fully understood, so it should only be used if the potential benefits outweigh the risks.
The safety and efficacy of deferasirox in children have not been fully established, and careful monitoring is required when administering this medication to pediatric patients.
It is not known whether deferasirox is excreted in human breast milk, and its effects on a nursing infant are unclear, so it should be used with caution while breastfeeding.
Deferasirox may cause dizziness or other side effects that could impair the ability to drive or operate machinery, so caution is advised when engaging in these activities.
Patients with pre-existing kidney conditions may require dose adjustments and close monitoring, as deferasirox can affect renal function.
Patients with pre-existing lung conditions should be monitored closely while taking deferasirox, as respiratory issues may arise.
Liver function should be monitored in patients taking deferasirox, as it can cause liver toxicity, and those with liver impairment may need dose adjustments.
Patients with cardiovascular issues should use deferasirox with caution, as it may have effects on heart function and requires monitoring.
Interactions between Asunra 400MG Tablet (6’s)
Asunra 400MG Tablet may interact with other medications, potentially affecting their efficacy or increasing the risk of side effects. Notable interactions include those with anticoagulants, certain antifungal agents, and medications that affect liver enzymes. Patients should inform their healthcare provider of all medications they are taking, including over-the-counter drugs and supplements, to avoid potential interactions.
How to store and dispose of Asunra 400MG Tablet (6’s)
To store Asunra 400MG Tablet properly, keep it in a cool, dry place away from direct sunlight and moisture. The medication should be stored at room temperature, ideally between 20°C to 25°C (68°F to 77°F). It is important to keep the tablets out of reach of children and pets. When disposing of unused or expired medication, do not flush it down the toilet or pour it down the drain. Instead, follow local guidelines for medication disposal or consult a pharmacist for safe disposal options.
Here are a few quick tips for Asunra 400MG Tablet (6’s)
Here are a few quick tips for using Asunra 400MG Tablet effectively and safely: always take the medication as prescribed by your healthcare provider, maintain a consistent daily schedule for taking the tablet, monitor for any side effects and report them to your doctor, keep regular appointments for blood tests to check iron levels and organ function, and avoid taking the medication with antacids or other medications that may interfere with its absorption.
Parameters that should be monitored Asunra 400MG Tablet (6’s)
While using Asunra 400MG Tablet, it is important to monitor certain parameters, including liver function tests, kidney function tests, and complete blood counts. Regular monitoring helps ensure that the medication is effectively reducing iron levels without causing significant adverse effects. Patients should also be vigilant for any signs of gastrointestinal bleeding or other unusual symptoms and report them to their healthcare provider promptly.
Considerations related to diet Asunra 400MG Tablet (6’s)
Dietary considerations while using Asunra 400MG Tablet include avoiding high-iron foods and supplements, as these can counteract the medication's effectiveness. Patients should also be cautious with calcium-rich foods and antacids, as they may interfere with the absorption of Deferasirox. A balanced diet rich in fruits, vegetables, and whole grains is recommended, and patients should consult their healthcare provider or a nutritionist for personalized dietary advice.
Question and Answer (FAQ)
Q: What is Asunra 400MG Tablet used for?
A: Asunra 400MG Tablet is used to treat chronic iron overload in patients who have received multiple blood transfusions.
Q: How does Asunra work?
A: Asunra works by binding to excess iron in the bloodstream, allowing it to be excreted from the body.
Q: What are the common side effects of Asunra?
A: Common side effects include gastrointestinal issues like diarrhea, nausea, and abdominal pain.
Q: Can I take Asunra with food?
A: Yes, Asunra can be taken with or without food, but it should be taken at the same time each day.
Q: What should I do if I miss a dose of Asunra?
A: If you miss a dose, take it as soon as you remember unless it's close to the next dose; do not double up.
Q: Is Asunra safe during pregnancy?
A: Asunra should be used with caution during pregnancy; consult your healthcare provider for advice.
Q: Can I drink alcohol while taking Asunra?
A: It is advisable to limit alcohol intake while using Asunra, as it can increase the risk of liver toxicity.
Q: How should I store Asunra?
A: Store Asunra in a cool, dry place away from direct sunlight and out of reach of children.
Q: What should I monitor while taking Asunra?
A: Regular monitoring of liver and kidney function, as well as iron levels, is essential while taking Asunra.
Q: Can children take Asunra?
A: Asunra should be used with caution in children, and dosing should be determined by a healthcare provider.
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