Tagrisso 80MG Tablet (10’s)
Tagrisso 80MG Tablet (10’s) is a targeted therapy medication primarily used in the treatment of non-small cell lung cancer (NSCLC) that has specific mutations in the epidermal growth factor receptor (EGFR) gene. The active ingredient in Tagrisso is Osimertinib, which is an oral tyrosine kinase inhibitor designed to selectively target and inhibit the activity of mutated forms of the EGFR protein. This medication is particularly effective for patients with advanced or metastatic NSCLC who have developed resistance to earlier EGFR inhibitors. Tagrisso is available in a convenient tablet form, with each tablet containing 80 mg of Osimertinib, making it easy for patients to incorporate into their daily routine. The drug works by blocking the signals that promote cancer cell growth and division, thereby slowing down the progression of the disease and improving overall survival rates.
Essential Drug Facts
| Dosage form | Oral Tablet |
|---|---|
| Chemical Class | M-Alkylindoles |
| Habit Forming | No |
| Systemic Category | Oncology |
| Action Class | Tyrosine kinase inhibitors |
What are the Indication / Medical Uses of Tagrisso 80MG Tablet (10’s)
Tagrisso 80MG Tablet (10's) is indicated for the treatment of patients with non-small cell lung cancer (NSCLC) that is positive for EGFR mutations, particularly those who have progressed on or after prior EGFR-targeted therapy. It is also used as a first-line treatment for patients with metastatic NSCLC harboring EGFR mutations. The drug is specifically beneficial for those with the T790M mutation, which is a common resistance mechanism that develops after treatment with other EGFR inhibitors.
How Does Tagrisso 80MG Tablet (10’s) Benefit You?
The benefits of Tagrisso 80MG Tablet (10's) for patients include improved progression-free survival and overall survival rates in individuals with advanced non-small cell lung cancer. By specifically targeting the mutated EGFR, Tagrisso can effectively reduce tumor size and slow disease progression, leading to an enhanced quality of life for patients. Additionally, the oral administration of the medication allows for greater convenience compared to intravenous therapies, making it easier for patients to adhere to their treatment regimen.
.svg)
Tagrisso 80MG Tablet (10’s) Action Mechanism
Tagrisso 80MG Tablet (10's) works by selectively inhibiting the activity of mutated forms of the epidermal growth factor receptor (EGFR) protein, which is often overactive in non-small cell lung cancer. By binding to the mutated EGFR, Osimertinib prevents the receptor from sending signals that promote cancer cell growth and survival. This targeted action not only helps to shrink existing tumors but also prevents the formation of new cancer cells, thereby controlling the progression of the disease.
How should Tagrisso 80MG Tablet (10’s) be used
To use Tagrisso 80MG Tablet (10's) properly, it is essential to follow the dosage instructions provided by a healthcare professional. The typical recommended dose is one tablet taken once daily, with or without food. It is important to swallow the tablet whole and not to crush or chew it, as this may affect the drug's effectiveness. Patients should adhere to the prescribed schedule and consult their doctor if they have any questions or concerns regarding their treatment.
When is the best time to take Tagrisso 80MG Tablet (10’s) ?
The best time to take Tagrisso 80MG Tablet (10's) is once daily, at the same time each day, to maintain consistent levels of the medication in the body. Whether taken in the morning or evening, it is crucial to establish a routine that fits the patient's lifestyle, as this can enhance adherence to the treatment plan. Patients should avoid taking the medication with food that is high in fat, as this may affect the absorption of the drug.
How does it affect me if I overdose?
In the event of an overdose of Tagrisso 80MG Tablet (10's), patients may experience severe side effects, including nausea, vomiting, diarrhea, and other gastrointestinal disturbances. Overdose can also lead to more serious complications, such as respiratory issues or severe skin reactions. If an overdose is suspected, it is critical to seek immediate medical attention to manage the symptoms and prevent further complications.
.svg)
How does it affect me if I miss a dose?
If a dose of Tagrisso 80MG Tablet (10's) is missed, patients should take the missed dose as soon as they remember, unless it is almost time for the next scheduled dose. In such cases, the missed dose should be skipped, and the regular dosing schedule should be resumed. Patients should not take two doses at once to make up for a missed dose, as this can increase the risk of side effects and complications.
Drug Adverse Reactions of Tagrisso 80MG Tablet (10’s)
Possible side effects and adverse reactions of Tagrisso 80MG Tablet (10's) may include diarrhea, rash, dry skin, and nausea. Some patients may also experience more severe reactions, such as interstitial lung disease, liver function abnormalities, or cardiac issues. It is important for patients to report any unusual symptoms or side effects to their healthcare provider promptly to ensure appropriate management.
Tagrisso 80MG Tablet (10’s) Tablet is contraindicated in following conditions
Tagrisso 80MG Tablet (10's) is contraindicated in patients with a known hypersensitivity to Osimertinib or any of the excipients in the formulation. Additionally, it should not be used in patients with severe liver impairment, as this may increase the risk of adverse effects and reduce the drug's effectiveness. A thorough medical history and assessment are essential before initiating treatment with Tagrisso.
Tagrisso 80MG Tablet (10’s) Safety Warnings and Precautions
While there are no direct contraindications, alcohol consumption may exacerbate side effects or interact with the medication, so moderation is advised.
Patients with a known hypersensitivity to Osimertinib or any of its components should avoid using this medication due to the risk of severe allergic reactions.
Osimertinib may cause harm to a developing fetus, and it is advised that women who are pregnant or planning to become pregnant avoid using this medication due to potential teratogenic effects.
The safety and efficacy of Osimertinib in pediatric patients have not been established, and its use in children is not recommended.
It is not known whether Osimertinib is excreted in human breast milk, and due to the potential for serious adverse effects in nursing infants, breastfeeding while on this medication is generally not recommended.
Osimertinib may cause side effects such as dizziness or fatigue, which could impair the ability to drive or operate machinery safely; patients should assess their individual response before engaging in such activities.
Patients with renal impairment may require dose adjustments or closer monitoring, as Osimertinib is primarily eliminated through the liver, but renal function can still impact drug levels.
Patients with a history of interstitial lung disease (ILD) or pneumonitis should be monitored closely, as Osimertinib can exacerbate these conditions.
Patients with hepatic impairment may experience altered drug metabolism, necessitating careful monitoring and potential dose adjustments to avoid toxicity.
Osimertinib can cause QT interval prolongation, which may lead to serious heart rhythm abnormalities; patients with pre-existing heart conditions should be monitored closely.
Interactions between Tagrisso 80MG Tablet (10’s)
Tagrisso 80MG Tablet (10's) may interact with other medications, potentially affecting their efficacy or increasing the risk of side effects. It is important for patients to inform their healthcare provider of all medications, supplements, and herbal products they are taking to avoid potential interactions. Specific drugs that may interact with Osimertinib include strong CYP3A4 inhibitors and inducers, which can alter the metabolism of the drug.
How to store and dispose of Tagrisso 80MG Tablet (10’s)
To store Tagrisso 80MG Tablet (10's) properly, keep the medication in its original packaging at room temperature, away from moisture and direct sunlight. It is essential to keep the tablets out of reach of children and pets. For disposal, unused or expired medications should be returned to a pharmacy or disposed of according to local regulations to prevent accidental ingestion or environmental contamination.
Here are a few quick tips for Tagrisso 80MG Tablet (10’s)
Here are a few quick tips for using Tagrisso 80MG Tablet (10's) effectively and safely: take the medication at the same time each day to maintain consistent levels in your system, do not crush or chew the tablets, and report any unusual side effects to your healthcare provider promptly. Additionally, maintain regular follow-up appointments for monitoring and discuss any concerns regarding your treatment plan with your doctor.
Parameters that should be monitored Tagrisso 80MG Tablet (10’s)
While using Tagrisso 80MG Tablet (10's), it is important to monitor specific parameters, including liver function tests, respiratory symptoms, and overall health status. Regular check-ups with a healthcare provider can help identify any potential side effects early and ensure the safe use of the medication.
Considerations related to diet Tagrisso 80MG Tablet (10’s)
Dietary considerations while using Tagrisso 80MG Tablet (10's) include avoiding high-fat meals around the time of taking the medication, as this may affect its absorption. Patients should maintain a balanced diet and stay hydrated, and consult their healthcare provider for personalized dietary recommendations during treatment.
Question and Answer (FAQ)
Q: What is Tagrisso used for?
A: Tagrisso is used to treat non-small cell lung cancer (NSCLC) with specific mutations in the epidermal growth factor receptor (EGFR) gene.
Q: How does Tagrisso work?
A: Tagrisso works by inhibiting the activity of mutated EGFR proteins, which helps to slow down cancer cell growth and division.
Q: What is the recommended dosage for Tagrisso?
A: The typical recommended dosage is one 80 mg tablet taken once daily, with or without food.
Q: What should I do if I miss a dose of Tagrisso?
A: If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not take two doses at once.
Q: What are the common side effects of Tagrisso?
A: Common side effects include diarrhea, rash, dry skin, and nausea. More severe reactions may occur, so report any unusual symptoms to your doctor.
Q: Can I take Tagrisso if I am pregnant?
A: Caution is advised during pregnancy, as the drug may pose risks to the developing fetus. Consult your healthcare provider for guidance.
Q: Is Tagrisso safe for breastfeeding mothers?
A: Caution is recommended for breastfeeding mothers, as it is unclear if Osimertinib is excreted in breast milk. Discuss with your doctor.
Q: Are there any dietary restrictions while taking Tagrisso?
A: It is advisable to avoid high-fat meals around the time of taking Tagrisso, as this may affect the drug's absorption.
Q: How should Tagrisso be stored?
A: Store Tagrisso at room temperature, away from moisture and sunlight, and keep it out of reach of children.
Q: What should I do if I overdose on Tagrisso?
A: If an overdose is suspected, seek immediate medical attention to manage symptoms and prevent complications.
Reviews
There are no reviews yet.