Duratia 60MG Tablet (10’s)

Duratia 60MG Tablet is a pharmacotherapeutic agent tailored for the treatment of premature ejaculation in men. This medication contains 60 milligrams of Dapoxetine Hydrochloride, a prominent member of the selective serotonin reuptake inhibitor (SSRI) family, although it is dispensed specifically for its off-label use in delaying ejaculation rather than for its antidepressant attributes. This dosage of Duratia 60MG Tablet offers an increase in the standard starting dose, often administered in cases where the lower dosage does not produce the desired therapeutic effect. Its rapid action and short half-life make it an appropriate on-demand treatment, notwithstanding the absence of a role in treating chronic depressive disorders due to its pharmacodynamics.

Essential Drug Facts

Dosage form	Oral Tablet
Chemical Class	Naphthalene Derivative
Habit Forming	No
Systemic Category	Genito - Urinary System
Action Class	Selective Seretonin Reuptake inhibitors (SSRIs)

What are the Indication / Medical Uses of Duratia 60MG Tablet (10’s)

Duratia 60MG Tablet is indicated for the treatment of PE (premature ejaculation) in men aged between 18 and 64 years who have all of the following conditions: a history of persistent or recurrent ejaculation with minimal sexual stimulation before, during, or shortly after penetration, and before the patient wishes and marked personal distress or interpersonal difficulty as a result of PE (premature ejaculation), and poor control over ejaculation.

How Does Duratia 60MG Tablet (10’s) Benefit You?

Duratia 60MG Tablet significantly improves the time before ejaculation and can increase control over ejaculation. This can reduce the distress and frustration that often accompanies premature ejaculation. In turn, sexual satisfaction may be improved for both the patient and their partner. The increased dosage available in Duratia 60MG provides a tailored response for men who need a more potent intervention.

Duratia 60MG Tablet (10’s) Action Mechanism

The primary constituent of Duratia 60MG, Dapoxetine Hydrochloride, functions by inhibiting the serotonin transporter, which leads to increased serotonin activity at pre- and post-synaptic receptors. As a result, ejaculatory delay is promoted. The amplification of synaptic activity in the central nervous system generates an enhanced and controlled ejaculatory response.

How should Duratia 60MG Tablet (10’s) be used

Duratia 60MG is taken orally, as needed, between 1-3 hours prior to anticipated sexual activity. It should not be taken more than once in 24 hours and can be taken with or without food. The tablet should be swallowed whole to avoid altering the release and absorption of the medication.

When is the best time to take Duratia 60MG Tablet (10’s) ?

The peak effectiveness of Duratia 60MG is reached when taken between 1-3 hours before engaging in sexual activity. This window allows the drug to reach sufficient plasma levels to be effective, providing the optimal balance between achieving the desired therapeutic effects and minimizing side effects.

How does it affect me if I overdose?

An overdose of Duratia 60MG can result in symptoms that may include severe dizziness, syncope, or other adverse cardiovascular effects. In such instances, immediate medical attention is warranted to address and mitigate any serious health implications.

How does it affect me if I miss a dose?

Omission of a scheduled dose of Duratia 60MG Tablet typically does not present significant consequences since the medication is used on an as-needed basis rather than on a routine schedule.

Drug Adverse Reactions of Duratia 60MG Tablet (10’s)

Adverse reactions may include nausea, dizziness, headaches, feeling weak, dyspepsia, insomnia, and sometimes more serious side effects like changes in mood, or even suicidal ideation. Persistent or significantly bothersome symptoms should prompt a medical consultation.

Duratia 60MG Tablet (10’s) Tablet is contraindicated in following conditions

It is imperative to note that the use of the active ingredient or any of the adjuncts may cause contraindications. These contraindications include heart issues, moderate to severe liver impairment, and patients taking Monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping treatment with an MAOI. It's also contraindicated for patients with a history of mania or severe depression, and those susceptible to seizures. It is, therefore, necessary for medical professionals to take these contraindications into account before prescribing the medication.

Duratia 60MG Tablet (10’s) Safety Warnings and Precautions

Alcohol:CAUTION

Can enhance side effects such as increased heart rate and dizziness.

Allergy:UNSAFE

Patients with known hypersensitivity should not use Duratia.

Pregnancy:UNSAFE

Not applicable as the drug is for male use only.

Children:UNSAFE

Duratia is not approved for individuals under 18.

Lactation:UNSAFE

Not applicable as the drug is for male use only.

Drive:CAUTION

Dizziness or altered attention due to Duratia may impair driving.

Kidney:CAUTION

Use caution in patients with renal impairment.

Lungs:CAUTION

Underlying pulmonary conditions necessitate careful prescription.

Liver:CAUTION

Patients with hepatic impairment should be given lower doses.

Heart:CAUTION

Cardiovascular status should be assessed before prescription.

Interactions between Duratia 60MG Tablet (10’s)

Potent CYP3A4 inhibitors like ketoconazole, atazanavir, and nefazodone, as well as serotonin reuptake inhibitors, monoamine oxidase inhibitors, thioridazine, and other serotoninergic agents.

How to store and dispose of Duratia 60MG Tablet (10’s)

Store Duratia 60MG at room temperature away from moisture and heat. Disposal should be through designated medicine take-back options, or by following specific home disposal instructions to prevent drug contamination in the environment.

Here are a few quick tips for Duratia 60MG Tablet (10’s)

Administering Duratia 60MG requires premeditated planning for sexual activity due to its on-demand usage. Users of Duratia 60MG Tablet should remain well-hydrated and avoid alcohol while on the medication. Caution is advised when operating heavy machinery, heavy work or driving, as side effects may include dizziness or altered cognitive function.

Parameters that should be monitored Duratia 60MG Tablet (10’s)

Clinicians should monitor the effect on ejaculatory delay, side effects, mental health symptoms, especially in patients with depression or other psychiatric conditions, and ensure that cardiovascular conditions are stable and compatible with sexual activity.

Considerations related to diet Duratia 60MG Tablet (10’s)

There are no specific dietary restrictions while taking Duratia 60MG, but a balanced diet contributes to overall health and well-being which is conducive to improved sexual function.